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老年乳头状甲状腺癌患者CT特征与颈部淋巴结转移关系

Association of computed tomography feature with cervical lymph node metastasis in elderly patients with papillary thyroid cancer

  • 摘要: 目的探讨老年乳头状甲状腺癌患者的X线计算机体层成像(CT)特征与颈部淋巴结转移的关系,为临床诊断提供参考依据。方法采用方便抽样方法对在北京市和辽宁省沈阳市4家医院2008年1月—2013年12月经手术病理证实的400例老年乳头状甲状腺癌患者进行CT检查。结果400例老年乳头状甲状腺癌患者中,259例患者发生颈部淋巴结转移,转移率为64.75%;发生颈部淋巴结转移患者肿瘤大小≥2 cm、病灶坏死、病灶周围侵犯、强化特点为重度的比例分别为83.40%、77.99%、97.89%、92.66%,均高于未发生颈部淋巴结转移患者的44.68%、63.12%、54.61%、59.57%,差异均有统计学意义(P<0.01)。结论老年乳头状甲状腺癌患者的CT特征可以初步判断颈部淋巴结是否发生转移。

     

    Abstract: ObjectiveTo assess the relationship between characteristic signs of computed tomography(CT)and cervical lymph node metastasis in elderly patients with papillary thyroid cancer.MethodsFrom January 2008 to December 2013,400 elderly patients with papillary thyroid cancer were selected from 4 hospitals.The relationship between characteristic signs of CT and cervical lymphnode metastasis was analysed.ResultsAmong the patients,there were 259(64.74%)with cervical lymph node metastasis.There were no statistically significant differences between the patients with metastasis and without metastasis in the number of tumors(χ2=0.60,P=0.44),tumor morphology(χ2=0.01,P=0.94),and calcification(χ2=0.86,P=0.35),but there were statistically significant differences in tumor size(χ2=64.86,P<0.01),necrosis(χ2=10.19,P<0.01),surrounding invasion(χ2=75.83,P<0.01),and enhancement on CT(χ2=64.95,P<0.01).ConclusionThe characteristic signs of tumor size,surrounding invasion and enhancement on CT may be the indications of cervical lymph node metastasis in elderly male patients with papillary thyroid cancer.

     

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