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新疆哈萨克族成人血脂异常及其影响因素

Prevalence of dyslipidemia and its influencing factors in Kazakh adults

  • 摘要: 目的 了解新疆哈萨克族≥18岁居民血脂异常现状及相关影响因素.方法 采用分层整群抽样方法,选取新疆新源县、石河子市等地区≥18岁哈萨克族居民3 935人进行调查问卷和身体检查,采集清晨空腹血样检测血脂;采用描述流行病方法和多因素logistic回归分析,分析哈萨克族居民血脂异常分布特征及其相关危险因素.结果 新疆哈萨克族居民总血脂异常患病率为40.9%,标化率为40.8%,其中高甘油三酯(TG)血症、高总胆固醇(TC)血症、高低密度脂蛋白胆固醇(LDL-c)血症、低高密度脂蛋白胆固醇(HDL-c)血症的患病率分别为19.4%、14.5%、7.7%、16.1%,标化率分别为18.7%、12.6%、6.3%、18.5%;男性血脂异常患病率为46.5%,高于女性的37.2%(χ2=33.865,P=0.000);血脂异常患病率随年龄增长的差异有统计学意义(χ2=33.682,P=0.000);多因素logistic回归分析显示,男性、超重肥胖是血脂异常的危险因素(分别OR=1.809,95%CI=1.307~2.503;OR=1.835,95%CI=1.329~2.535);饮奶茶量、蔬菜水果类是血脂异常的保护因素(分别OR=0.588,95%CI=0.463~0.746;OR=0.591,95%CI=0.419~0.835).结论 新疆哈萨克族成人各项血脂异常患病率均高于全国平均水平,以高TG血症、低HDL-c血症为主;血脂异常患病率年轻化趋势明显.

     

    Abstract: Objective To assess the prevalence of lipid disorders and its related risk factors among Kazakh adults aged 18 years and older.Methods Stratified cluster sampling was adopted to select 3 935 Kazakh adults aged 18 years and older in Xinyuan country,Shihezi city and other regions for a questionnaire survey and physical examination.Fasting blood samples were collected for serum lipids detection.Descriptive epidemiological method and multivariate logistic regression analysis were used to analyze the prevalence of dyslipidemia and its risk factors.Results The total prevalence of dyslipidemia among the adults was 40.9%,with a standardized rate of 40.8%.The prevalence rates of hypertriglycerdemia,high total cholesterol(TC),high low-density lipoprotein cholesterol(LDC-c),and lowhigh-density lipoprotein cholesterol(HDL-c)were 19.4%,14.5%,7.7%,and 16.1%,with the standardized rates of 18.7%,12.6%,6.3%,and 18.5%,respectively.The prevalence of dyslipidemia in the males was 46.5%,higher than that of the females(37.2%,χ2=33.865; P=0.000).Multivariate logistic regression analyses showed that gender and body mass index(BMI)were risk factors of dyslipidemia(odds ratioOR=1.809,95% confidence intervalCI:1.307-2.503; OR=1.835,95% CI=1.329-2.535).The amount of tea drinking,intakes of vegetables and fruits were protective factors for dyslipidemia(OR=0.588,95% CI:0.463-0.746; OR=0.591,95% CI:0.419-0.835).Conclusion The prevalence of dyslipidemia in Kazakh adults was higher than that of the national average,especially for high hypertriglyceridemia and lowHDL-c hyperlipidemia.The prevalence of dyslipidemia demonstrates an increase trend among the young adults.

     

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